Donna

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Is the neutrophil a ‘prima donna’ in the procoagulant process during sepsis?

Activation of the coagulation system is a fundamental host defense mechanism. Microorganisms that have invaded the body are trapped and disposed of in clots. Monocytes/macrophages are widely accepted as the main players in the procoagulant process; however, recent evidence suggests that neutrophils also play important roles. Tissue factor, which initiates the extrinsic coagulation cascade, is r...

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, Donna Rose Addis and Daniel L . Schacter Memory for Emotional Simulations : Remembering a Rosy Future

Mental simulations of future experiences are often concerned with emotionally arousing events. Although it is widely believed that mental simulations enhance future behavior, virtually nothing is known about how memory for these simulations changes over time or whether simulations of emotional experiences are especially well remembered. We used a novel paradigm that combined recently developed ...

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The prima donna of epigenetics: the regulation of gene expression by DNA methylation.

This review focuses on the mechanisms of DNA methylation, DNA methylation pattern formation and their involvement in gene regulation. Association of DNA methylation with imprinting, embryonic development and human diseases is discussed. Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in tr...

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Donna M. Randall Leadership and the Use of Power: Shaping an Ethical Climate

Leaders have several tools at their disposal to reinforce an ethical work climate. Five sources of power available to leaders are explored. These sources of power fall into the two broad categories of positional power and personal power. It is hypothesized that personal power may be more effective than positional power in promoting ethical conduct. Specific suggestions for the most effective us...

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Donna K . Arnett and Joseph Loscalzo Report of the Basic Science Writing Group

Report of the Basic Science Writing Group Discovering the Full Spectrum of Cardiovascular Disease : Minority Health Summit 2003: Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.0000157741.99920.0C 2005;111:e...

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ژورنال

عنوان ژورنال: Science

سال: 1960

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.132.3432.923